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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PGAM5
All Species:
13.33
Human Site:
Y92
Identified Species:
24.44
UniProt:
Q96HS1
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96HS1
NP_612642.1
289
32004
Y92
L
A
S
K
L
D
H
Y
K
A
K
A
T
R
H
Chimpanzee
Pan troglodytes
XP_509498
465
51564
Y92
L
A
S
K
L
D
H
Y
K
A
K
A
T
R
H
Rhesus Macaque
Macaca mulatta
XP_001083353
235
26735
A42
L
D
H
Y
K
A
K
A
T
R
H
I
F
L
I
Dog
Lupus familis
XP_543346
289
31978
C92
L
A
S
R
L
D
H
C
K
A
K
A
T
R
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8BX10
288
31976
Y91
L
T
S
R
L
D
H
Y
K
A
K
A
T
R
H
Rat
Rattus norvegicus
Q562B5
288
32042
Y91
L
A
S
R
L
D
H
Y
K
A
K
A
T
R
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510978
229
26244
K36
K
L
E
H
H
K
A
K
A
T
R
H
I
F
L
Chicken
Gallus gallus
XP_415083
212
24106
A19
L
E
H
C
R
A
R
A
T
R
H
I
F
L
I
Frog
Xenopus laevis
Q5FWM4
275
30968
H79
L
Q
L
H
L
N
K
H
K
P
K
A
T
R
H
Zebra Danio
Brachydanio rerio
Q502L2
289
32155
N92
G
S
Q
D
A
E
N
N
K
P
R
A
T
R
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O46084
289
33147
A81
Y
N
A
E
L
E
K
A
K
A
K
K
A
R
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09422
284
32472
I86
E
E
G
K
K
K
L
I
E
E
K
K
A
T
A
Sea Urchin
Strong. purpuratus
XP_793164
286
31924
V88
P
T
T
K
L
T
G
V
K
P
T
A
T
R
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
61.7
79.9
93
N.A.
93.4
92.7
N.A.
70.9
64.3
65
64.7
N.A.
46
N.A.
42.5
53.6
Protein Similarity:
100
62.1
81.3
97.5
N.A.
96.1
96.8
N.A.
76.8
70.5
78.1
77.1
N.A.
61.9
N.A.
59.1
67.1
P-Site Identity:
100
100
6.6
86.6
N.A.
86.6
93.3
N.A.
0
6.6
53.3
33.3
N.A.
40
N.A.
13.3
46.6
P-Site Similarity:
100
100
6.6
93.3
N.A.
93.3
100
N.A.
6.6
6.6
66.6
60
N.A.
60
N.A.
20
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
31
8
0
8
16
8
24
8
47
0
62
16
0
8
% A
% Cys:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
8
0
39
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
16
8
8
0
16
0
0
8
8
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
16
8
0
% F
% Gly:
8
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% G
% His:
0
0
16
16
8
0
39
8
0
0
16
8
0
0
70
% H
% Ile:
0
0
0
0
0
0
0
8
0
0
0
16
8
0
16
% I
% Lys:
8
0
0
31
16
16
24
8
70
0
62
16
0
0
0
% K
% Leu:
62
8
8
0
62
0
8
0
0
0
0
0
0
16
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
8
8
8
0
0
0
0
0
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
24
0
0
0
0
0
% P
% Gln:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
24
8
0
8
0
0
16
16
0
0
70
0
% R
% Ser:
0
8
39
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
16
8
0
0
8
0
0
16
8
8
0
62
8
0
% T
% Val:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
8
0
0
0
31
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _